In Russia in order to prove a generic drug bioequivalence, a comparison of pharmacokinetics profile in human is used, whereas dissolution test in vitro in other countries is also applied. If development of generic drug is in process we can test the samples bioequivalence in animal evaluation of pharmacokinetics profile of the drugs. To test bioequivalence in human we select an authorized clinic and insure volunteers and management of the study. We also insure all procedures supervision during clinical trials in frame of GCP and Russian regulation. Then obtained data are analyzed, and company’s experts prepare the report of the study.